Com.pl.i.t DX® Colon
The Com.pl.it DX® Colon multi-gene test encompasses genes with mutations linked to colorectal cancer. Analyzing many genes is crucial for devising a personalized therapy strategy for colorectal cancer patients.
It ascertains the molecular profile (gene mutations) of the tumor and the relationships among genes in instances of numerous mutations.
Identifies on-label pharmaceuticals that target either the mutant genes or the associated pathways.
It identifies variants linked to resistance against targeted medicines.
Advocates for off-label medications or treatments in clinical trials informed by the tumor’s molecular characteristics. This may be especially significant for people for whom regular treatment has been ineffective.
| 79 DNA Genes | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ABL1 | AKT1 | ALK | APC | ARAF | ATM | BRAF | BRCA2 | CCNE1 | CDH1 |
| CDKN2A | CSF1R | CTNNB1 | DDR2 | DICER1 | EGFR | EIF1AX | ERBB2 | ERBB3 | ERBB4 |
| EZH1 | EZH2 | FBXW7 | FGFR1 | FGFR2 | FGFR3 | FLT3 | FOXL2 | GNA11 | GNAQ |
| GNAS | HNF1A | HRAS | IDH1 | IDH2 | JAK2 | JAK3 | KDR | KEAP1 | KIT |
| KRAS | MAP2K1 | MDM2 | MET | MLH1 | MPL | MYC | NOTCH1 | NPM1 | NRAS |
| NTRK1 | NTRK2 | NTRK3 | PDGFRA | PIK3CA | POLE | PTEN | PTPN11 | RAC1 | RAF1 |
| RB1 | RET | ROS1 | RC | SMAD4 | SMARCB1 | SMO | SOS1 | SPOP | STK11 |
| TERT | TP53 | VHL | |||||||
| 18 RNA Genes | |||||
|---|---|---|---|---|---|
| ALK | BRAF | EGFR | ERG | FGFR2 | FGFR3 |
| MET | NRG1 | NTRK1 | NTRK2 | NTRK3 | PBX1 |
| PPARG | PRKACA | RAF1 | RET | ROS1 | TFE3 |
| Immunohistochemistry | ||
|---|---|---|
| PD-L1 | HER2 | c-MET |
Seven gene rearrangements
ALK MET ROS1 RET NTRK1 NTRK2 NTRK3
Biomarkers for immunotherapy
MSI
Immunohistochemical Biomarkers
HER2
Exemplary Results Report
It is intended for individuals diagnosed with colorectal cancer. It may also be applicable to various forms of solid tumors, particularly those of indeterminate origin.
Results for Com.Pl.i.t DX® Colon will be provided within 10 business days following the receipt of the sample.
For the study of Com.Pl.i.t.DX® colon, we require the paraffin block from the tumor or, alternatively, uncolored paraffin sections mounted on slides (air-dried, not oven-dried). Specifically, we require four portions of 3μm and six sections of 10μm.
The specimen must be maintained at ambient temperature (25 °C). We advise including an ice pack in the bag throughout the summer season, ensuring it does not come into direct contact with the samples or papers
The Customer Service Department will issue a distinct e-banking payment code, or payment may be executed via bank transfer.
sacipharm is accountable for the requisite procedures regarding the receipt and return of your sample. Please contact us to coordinate sample collection and return.
Your results will be transmitted to your physician through a secure network and to you via email, accompanied by a secure unique code supplied by customer support.
Our Customer Service Team is dedicated to addressing your inquiries concerning the services provided by Scipharm. For inquiries regarding the ordering of any tests, please contact us directly.
To finalize the test, you must complete and submit the Consent form available at the link below.
